Skip to main content
. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Virchows Arch. 2019 Jun 17;475(5):537–549. doi: 10.1007/s00428-019-02601-0

Figure 4.

Figure 4.

Differential diagnostic considerations for usual-type HPVA. (A) Usual-type endocervical adenocarcinoma can exhibit pseudoendometrioid morphology, mimicking the appearance of (B) endometrioid endometrial adenocarcinoma, but will also have floating mitoses, apoptotic debris, and will be negative for estrogen receptor. Usual-type endocervical adenocarcinoma can also exhibit slit-like spaces (C), thin/fine papillary archiecture (D) or broad papillary architecture (E), mimicking the appearance of endometrial serous adenocarcinoma (F), but it will be negative for p53 and HPV.