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Animal challenge study of immunized and non-immunized mice. Survival of immunized mice with PspA fragments after a challenge with pneumococcal strain containing PspA from clade 2 was investigated. Survival was inspected 21 days after the challenge.
| Mice group | No. of challenged mice (Survived/Total) |
P value |
|---|---|---|
| PspA4ABC | 2/5 | 0.155 |
| PspAB1-5 | 5/5 | 0.001 |
| Alum (negative control) | 0/5 | --- |
