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. 2019 Nov 5;24(21):4006. doi: 10.3390/molecules24214006

Figure 4.

Figure 4

(A) Ajoene has inspired derivatives synthesis like (B) (E,Z)-1,8-(Bis-para-methoxyphenyl)-2,3,7-trithia-octa-4-ene [73], and (C) SPA3015 [74], molecules with anti-proliferative effects in cancer cells. Other studies have produced (D) a labelled dansyl and (E) fluorescein ajoene derivatives to assist in the identification of molecular targets prone to ajoene modification in mammalian cells [75,76].