Table 3. Effect of ethanolic extract of Emblica officinalis on vascular chemistry (MDA, Vitamin C and E, NO and NOS3).
| Parameter | Group I | Group II | Group III | Group IV | ANOVA | |
|---|---|---|---|---|---|---|
| F Value | p Value | |||||
| MDA (µM/L) | 0.47 ± 0.6 | 1.03 ± 0.13 | 3.05 ± 0.5a,b | 1.3 ± 0.2c | 30.4 | 0.000* |
| Vitamin C (mg/dl) | 5.2 ± 0.4 | 7.08 ± 0.3a | 5.8 ± 0.32-b | 6.4 ± 0.4 | 4.4 | 0.025* |
| Vitamin E (µg/ml) | 5.8 ± 0.5 | 6 ± 0.4 | 5 ± 0.9b | 5.5 ± 0.8 | 10.8 | 0.04* |
| NO (µM/L) | 3.8 ± 0.49 | 7.2 ± 0.69a | 2.9 ± 0.6b | 4.9 ± 0.8b,c | 22.29 | 0.000* |
| NOS3 (ng/ml) | 30.7 ± 1.7 | 29.5 ± 1.07 | 31.1 ± 1.9 | 31.3 ± 0.9 | 0.855 | 0.489 |
Values are expressed as mean ± SD. ANOVA followed by ‘Post hoc t’ test. Group I: control, group II: supplemented with ethanolic extract of Emblica officinalis, group III: high fat fed rats, group IV: high fat diet + ethanolic extract of Emblica officinalis. Superscript a, b, c express significant difference between groups. ‘a’ depicts comparison with group I, ‘b’ depicts a comparison with group II, ‘c’ depicts a comparison with group III.(*p ≤0.05).