Table 2.
Metabolic pathway analysis with MetaboAnalyst from differential lipid species.
| Pathway Name | Total | Hits | Impact | Raw p | FDR | −log(p) |
|---|---|---|---|---|---|---|
| Glycerophospholipid metabolism | 30 | 3 | 0.254 | 0.000 | 0.024 | 8.137 |
| Glycerolipid metabolism | 18 | 1 | 0.107 | 0.087 | 1 | 2.446 |
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | 14 | 1 | 0.044 | 0.068 | 1 | 2.689 |
| Linoleic acid metabolism | 5 | 1 | 0.000 | 0.025 | 1 | 3.699 |
| alpha-Linolenic acid metabolism | 9 | 1 | 0.000 | 0.044 | 1 | 3.120 |
| Sphingolipid metabolism | 21 | 1 | 0.000 | 0.100 | 1 | 2.298 |
| Arachidonic acid metabolism | 36 | 1 | 0.000 | 0.167 | 1 | 1.791 |
Total: The total number of metabolites in the pathway. Hits: The actually matched number from the differential lipid species. Impact: The pathway impact value calculated from pathway topology analysis. Raw p: Original p value calculated from the enrichment analysis. FDR: The p value adjusted using the false discovery rate.