Table 1.
Compound | Activity | Ref. | |
---|---|---|---|
G. lamblia [IC50 (µg/mL)] |
[61] | ||
7 | 4.62 ± 0.12 | ||
MTZ | 0.86 ± 0.03 | ||
G. lamblia [IC50 (µg/mL)] |
[62] | ||
8 | 84.2 | ||
MTZ | 1.22 | ||
G. intestinalis [IC50 (µM)] |
[63] | ||
9a | 0.122 | ||
9b | 0.151 | ||
Aminitrozole | 0.490 | ||
MTZ | 5.360 | ||
G. lamblia [IC50 (µM)] |
[64] | ||
10 | 19.58 | ||
MTZ | 62.48 | ||
G. lamblia [IC50 (µg/mL)] |
[65] | ||
11 | 30.6 | ||
MTZ | 0.21 | ||
G. intestinalis [IC50 (µM)] |
[66] | ||
12a | 0.027 ± 0.002 | ||
12b | 0.022 ± 0.001 | ||
12c | 0.027 ± 0.002 | ||
12d | 0.021 ± 0.005 | ||
Nitazoxamide | 0.015 ± 0.002 | ||
Mebendazole | 0.046 ± 0.009 | ||
MTZ | 1.224 ± 0.021 | ||
G. duodenalis [IC50 (µg/mL)] |
[67] | ||
13a | 14.3 | ||
13b | 8.2 | ||
MTZ | 11.4 | ||
G. intestinalis [IC50 (µM)] |
[68] | ||
14a | 0.87 | ||
14b | 0.39 | ||
MTZ | 1.40 | ||
G. lamblia [IC50 (µM)] |
[69] | ||
Disulfiram (15) | 6.6 |