Figure 2.

Motifs present in the $\alpha$-CA family. (A) Web logo presenting residue conservation within a motif in each sequence and a heat map showing motif conservation as the number of motif sites per total number of protein sequences. A value of zero is for motifs that are not conserved in any sequence, whereas a value of 1 shows that motif exists in all selected sequences. The prefix ’M’ represents the word “motif”. (B) Motif location in 3D space within CA-II. The grey sphere represents the Zn${}^{2+}$. Representations were generated using Schrödinger Maestro and Inkscape.