Table 3.
Variant | Imidazole-Zn Distance (Å) | ||||||||
---|---|---|---|---|---|---|---|---|---|
apo | BCT | CO | |||||||
In | Out | Faux in | In | Out | Faux in | In | Out | Faux in | |
K18E | 8.65 | * | 7.30 | 8.08 | 11.09 | * | 6.96 | 11.20 | * |
K18Q | 8.11 | 11.01 | * | 8.22 | * | * | 8.96 | 10.42 | * |
H107Y | 8.50 | 10.63 | * | 8.24 | 10.86 | * | 7.98 | 10.67 | * |
P236H | 8.57 | 11.26 | * | 8.70 | 12.02 | * | 7.12 | 11.71 | * |
P236R | 8.26 | 11.02 | 7.36 | 7.99 | 10.84 | * | 7.50 | 10.43 | * |
N252D | 8.11 | 11.33 | * | 8.65 | 10.93 | * | 8.63 | 11.20 | * |
WT | 8.24 | 11.21 | * | 8.57 | 11.07 | * | 8.45 | 11.31 | * |
* Conformation not observed.