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RNA-seq analysis results and verification. (A) Venn map of the number of significantly differentially expressed genes. (B) Hot map of gene expression related to insulin-like growth factor pathway. (C) Real-time PCR of IGFBP-7. Real-time PCR demonstrate that treatment of eleutheroside B largely blocked upregulated mRNA levels of IGFBP-7. *** p < 0.001, ### p < 0.001.
