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PDGF D regulates androgen receptor (AR) expression. Parental murine PTEN wildtype (PTEN+/+), PTEN knockout (PTEN−/−), and PTEN−/− expressing scrambled (shScrm) or PDGF D shRNA (shPDGF D) prostate epithelial cells were subjected to immunoblot (A), qualitative RT-PCR (B) and quantitative RT-PCR (C-D) analyses to determine the levels of AR and its target gene NKx13.l.
