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. 2019 Oct 25;24(21):3853. doi: 10.3390/molecules24213853

Table 6.

Minimal inhibitory (MIC) and fungicidal (MFC) concentration values of the proposed (18) compounds (μmol·mL−1).

Aspergillus fumigatus
Clinical Isolate
Aspergillus fumigatus
ATCC 204305
Compound MIC MFC MIC MFC
1 0.2024 ± 0.001d 0.4047 ± 0.002c 0.1012 ± 0.001d 0.4047 ± 0.003d
2 0.2028 ± 0.001d 0.4056 ± 0.002c 0.0507 ± 0.0008c 0.1014 ± 0.001c
3 0.2096 ± 0.001d 0.4192 ± 0.003c 0.2096 ± 0.001e 0.4192 ± 0.002d
4 0.1190 ± 0.001c 0.4762 ± 0.003d 0.2381 ± 0.001e 0.4762 ± 0.002e
5 0.2083 ± 0.001d 0.4166 ± 0.002c 0.2083 ± 0.001e 0.4166 ± 0.002d
6 0.2053 ± 0.001d 0.4106 ± 0.002c 0.2053 ± 0.002e 0.4106 ± 0.003d
7 0.2693 ± 0.001e 0.5386 ± 0.004d 0.2693 ± 0.001f 0.5386 ± 0.004e
8 0.1986 ± 0.001d 0.3972 ± 0.002c 0.1986 ± 0.001e 0.3972 ± 0.002d
Ketoconazole 0.0023 ± 0.00002b 0.0046 ± 0.00004b 0.0023 ± 0.00001b 0.0046 ± 0.00004b
Econazole 0.1754 × 10−3 ± 0.01 ×10−3a 0.3508 × 10−3 ± 0.02 × 10−3a 0.0877 × 10−3 ± 0.002 × 10−3a 0.1754 × 10−3 ± 0.002 × 10−3a

Experiments were performed in duplicate and repeated three times. Values are expressed as means ± SD. In each column, different letters mean significant differences between samples (p < 0.05).