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. 2015 May 1;2015(5):CD011681. doi: 10.1002/14651858.CD011681
Date Event Description
8 April 2016 Amended Affiliation added for LM.
30 April 2015 Review declared as stable This review will be assessed for further updating in 2020.
24 November 2014 New citation required and conclusions have changed This is the update of the 'Selective serotonin re‐uptake inhibitors (SSRIs) for preventing migraine and tension‐type headaches' review. However, the following major changes have been implemented:
  • the intervention includes selective‐serotonin and serotonin‐norepinephrine reuptake inhibitors;

  • the population is adults with episodic and chronic tension‐type headache;

  • migraine is the topic of another Cochrane review;

  • the search strategy was revised to account for these changes and updated in November 2014.


We included two new studies (120 participants) in this update ( Singh 2002; Zissis 2007). Overall, we included eight studies and 412 participants. We recommend previous readers of the review should re‐read this update.
7 April 2014 New search has been performed We have updated this review to include the results of a new search and to include a new class of antidepressants (serotonin‐norepinephrine reuptake inhibitors). We have added a study flow chart, 'Risk of bias' tables, and 'Summary of findings' tables.
10 August 2009 Amended Contact details updated.
28 October 2008 Amended Converted to new review format.