Gabrielidou 1998.

Methods	Randomised, double‐blind cross‐over study Country: Greece
Participants	20 subjects (16 female; 4 male) with tension‐type headache according to the International Headache Society Criteria (IHS 2004); mean age 38 ± 18 More than 10 attacks per month, significant disturbance in quality of life, refractory headache attacks, ability to keep a diary
Interventions	1. Amitriptyline 50 mg/day 2. Venlafaxine 100 mg/day Active treatment duration: 8 weeks
Outcomes	Headache frequency, intensity, and duration Quality of life Hamilton and Beck Anxiety and Depression Rating Scales
Notes	Washout period: one week