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. Author manuscript; available in PMC: 2019 Nov 20.
Published in final edited form as: Clin Cancer Res. 2018 May 24;24(16):3820–3828. doi: 10.1158/1078-0432.CCR-17-3348

Figure 4.

Figure 4.

In the time-escalation arm, γH2AX expression, phosphohistone-3 expression (PH3), and CC3 expression all demonstrated peak changes 8 hours following AZD1775 administration. Horizontal line marks the mean fold change.