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. 2019 Nov 20;16:230. doi: 10.1186/s12974-019-1627-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of elamipretide (SS-31) on neural cell apoptosis in mice with hippocampal impairment. a, b TUNEL staining demonstrated neural cell apoptosis in the DG and CA1 regions of the hippocampus from indicated group of mice. c, d The number of hippocampal apoptotic neural cells in the DG and CA1 regions of the hippocampus from indicated group of mice. Scale bars: 50 μm. Data are expressed as the mean ± SE (n = 6). ***P < 0.001 vs. CON group; ##P < 0.01 vs. LPS group. SS-31 elamipretide, aCSF artificial cerebrospinal fluid, LPS lipopolysaccharide, SE standard error