Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structures of representative PKM2 activators.
| PKM2 activators | Structures | (Refs.) |
|---|---|---|
| Micheliolide |  |
(31) |
| Diarylsulfonamides |  |
(29) |
| Thieno[3,2-b]pyrrole[3,2-d]pyridazinones |  |
(32) |
| 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide |  |
(33) |
| TEPP-46 |  |
(34) |
| 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones |  |
(30) |
| 1-(sulfonyl)-5-(arylsulfonyl)indoline |  |
(35) |
PKM2, pyruvate kinase isoenzyme M2.
