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. 2019 Oct 2;18(6):5663–5672. doi: 10.3892/ol.2019.10948

Table II.

Effect of pyruvate kinase isoenzyme M2 on cisplatin sensitivity in different cancers.

Cancer type Effect Treatment (Refs.)
Bladder cancer Overcomes resistance Shikonin (76,79)
Hepatocellular carcinoma Chemosensitivity MicroRNA-199a (80)
Osteosarcoma Chemosensitivity Metformin (47)
Cervical cancer Chemosensitivity PKM2 (18)

PKM2, pyruvate kinase isoenzyme M2.