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. 2019 Sep 25;18(6):5769–5784. doi: 10.3892/ol.2019.10922

Table IV.

Enriched Kyoto Encyclopedia of Genes and Genomes pathway analysis of 158 differentially expressed mRNAs.

Term Count P-value Genes
bta04151:Phosphoinositide-3-kinase-protein kinase B signaling pathway 10 6.79 ×10−04 COL4A1, SGK2, COL6A3, COL1A2, COL1A1, THBS1, COL11A1, THBS2, FN1, SPP1
bta04510:Focal adhesion 9 9.84 ×10−05 COL4A1, COL6A3, COL1A2, COL1A1, THBS1, COL11A1, THBS2, FN1, SPP1
bta05146:Amoebiasis 6 0.001142 COL4A1, COL1A2, CXCL8, COL1A1, COL11A1, FN1
bta05144:Malaria 3 0.054453 CXCL8, THBS1, THBS2
bta01100:Metabolic pathways 16 0.024433 CYP3A5, PIK3C2G, CYP2C18, ACER2, ADH1C, ADH7, FBP2, AMPD1, ALDH3A1, RDH12, AKR1B10, MGAM, TPH1, SMPD3, LIPF
bta04512:Extracellular matrix-receptor interaction 9 1.47 ×10−07 COL4A1, COL6A3, COL1A2, COL1A1, THBS1, COL11A1, THBS2, FN1, SPP1
bta04971:Gastric acid secretion 7 1.07 ×10−05 KCNJ16, KCNJ15, ATP4A, ATP4B, SLC26A7, KCNE2, CA2
bta04974:Protein digestion and absorption 7 2.61 ×10−05 COL4A1, COL6A3, COL1A2, COL12A1, COL1A1, COL11A1, COL10A1
bta00830:Retinol metabolism 6 4.79 ×10−05 RDH12, CYP3A5, CYP2C18, ADH1C, ADH7
bta05204:Chemical carcinogenesis 6 1.29 ×10−04 CYP3A5, CYP2C18, ADH1C, ADH7, ALDH3A1
bta00140:Steroid hormone biosynthesis 4 0.007616 CYP3A5, STS, CYP2C18
bta00010:Glycolysis/Gluconeogenesis 4 0.010031 ADH1C, ADH7, FBP2, ALDH3A1
bta04966:Collecting duct acid secretion 3 0.015591 ATP4A, ATP4B, CA2
bta00591:Linoleic acid metabolism 3 0.028276 CYP3A5, CYP2C18
bta00350:Tyrosine metabolism 3 0.032672 ADH1C, ADH7, ALDH3A1
bta00982:Drug metabolism-cytochrome P450 3 0.063878 ADH1C, ADH7, ALDH3A1
bta00980:Metabolism of xenobiotics by cytochrome P450 3 0.065826 ADH1C, ADH7, ALDH3A1