Table 1. Patient Characteristics of All Patients Undergoing Transoral Surgery for p16-Positive BOT OPSCC.
| Variable | Patient Group, No. (%)a | P Value | |
|---|---|---|---|
| Unilateral (n = 113) | Bilateral (n = 89) | ||
| Sex | |||
| Male | 96 (85.0) | 81 (91.0) | .62 |
| Female | 12 (10.6) | 8 (9.0) | |
| Smoking | |||
| Never | 59 (52.2) | 37 (41.6) | .28 |
| Past | 39 (34.5) | 37 (41.6) | |
| Current | 14 (12.4) | 15 (16.9) | |
| Comorbidity | |||
| None | 54 (47.8) | 30 (33.7) | .01 |
| Mild | 47 (41.6) | 38 (42.7) | |
| Moderate | 6 (5.3) | 17 (19.1) | |
| Severe | 5 (4.4) | 4 (4.5) | |
| Tumor location | |||
| Lateralized | 65 (57.5) | 42 (47.2) | |
| Crossed midline | 37 (32.7) | 41 (46.1) | .17 |
| Unknown | 10 (8.8) | 6 (6.7) | |
| Clinical T stage | |||
| T0 | 21 (18.6) | 18 (20.2) | .72 |
| T1 | 39 (34.5) | 24 (27.0) | |
| T2 | 34 (30.1) | 27 (30.3) | |
| T3 | 13 (11.5) | 12 (13.5) | |
| T4 | 6 (5.3) | 8 (9.0) | |
| Clinical N stage | |||
| N0 | 15 (13.3) | 5 (5.6) | .02 |
| N1 | 74 (65.5) | 51 (57.3) | |
| N2 | 20 (17.7) | 31 (34.8) | |
| N3 | 4 (3.5) | 2 (2.2) | |
| Clinical contralateral nodal disease | |||
| No | 93 (82.3) | 70 (78.7) | .60 |
| Yes | 20 (17.7) | 19 (21.3) | |
| Pathologic T stage | |||
| T1 | 50 (44.2) | 32 (36.0) | .18 |
| T2 | 41 (36.3) | 34 (38.2) | |
| T3 | 15 (13.3) | 11 (12.4) | |
| T4 | 5 (4.4) | 12 (13.5) | |
| Unknown | 2 (1.8) | 0 | |
| Pathologic N stage | |||
| N0 | 9 (8.0) | 4 (4.5) | .12 |
| N1 | 86 (76.1) | 63 (70.8) | |
| N2 | 14 (12.4) | 22 (24.7) | |
| Unknown | 4 (3.5) | 0 | |
| Adjuvant therapy | |||
| None | 21 (18.6) | 17 (19.1) | .08 |
| Radiotherapy | 57 (50.4) | 36 (40.4) | |
| Chemoradiotherapy | 30 (26.5) | 35 (39.3) | |
| Unknown | 4 (3.5) | 0 | |
Abbreviations: BOT, base of tongue; OPSCC, oropharyngeal squamous cell carcinoma.
a
Percentages have been rounded and may not total 100. Data were missing for 1 patient in the unilateral group for all variables except for clinical and pathologic data and for 1 patient in the bilateral group for adjuvant therapy.