Table 1. Baseline Characteristics of Participants.
| Characteristic | Patients, No. (%) | ||
|---|---|---|---|
| Near Infrared–Induced Autofluorescence (n = 121) | Standard Care (n = 120) | Total (N = 241) | |
| Preoperative Variables | |||
| Sex | |||
| Male | 25 (20.7) | 24 (20.0) | 49 (20.3) |
| Female | 96 (79.3) | 95 (79.2) | 191 (79.3) |
| Not determined | 0 | 1 (0.8) | 1 (0.4) |
| Age, median (IQR), y | 52.5 (46.0-63.0) | 51.0 (45.0-64.0) | 52.0 (45.0-64.0) |
| BMI, median (IQR) | 27.0 (22.5-30.0) | 26.5 (23.0-30.5) | 27.0 (23.0-30.0) |
| Preoperative corrected calcium, median (IQR), mg/dL | 9.30 (9.10-9.50) | 9.30 (9.03-9.50) | 9.30 (9.10-9.50) |
| Preoperative parathyroid hormone, median (IQR), pg/mL | 48.5 (41.0-66.0) | 45.0 (35.0-65.5) | 47.0 (38.0-66.0) |
| Diagnosis | |||
| Cancer | 20 (16.5) | 18 (15.0) | 38 (15.8) |
| Multinodular goiter | 63 (52.1) | 73 (60.8) | 136 (56.4) |
| Toxic multinodular goiter | 4 (3.3) | 8 (6.7) | 12 (5.0) |
| Graves disease | 33 (27.3) | 20 (16.7) | 53 (22.0) |
| Thyroiditis | 0 | 1 (0.8) | 1 (0.4) |
| Not determined | 1(0.8) | 0 | 1(0.4) |
| Operative Variables | |||
| Duration of operation, median (IQR), min | 99 (88-114) | 91 (77-103) | 94 (81-107) |
| Patients who were operated on per center, No. | |||
| 1 | 97 | 99 | 196 |
| 2 | 16 | 16 | 32 |
| 3 | 8 | 5 | 13 |
| Postoperative Variables | |||
| Specimen weight, median (IQR), g | 41.1 (24.0-68.0) | 35.6 (23.4-58.0) | 37.1 (24.0-64.5) |
| Size of the largest nodule, median (IQR), mm | 21.5 (13.5-35.0) | 25.0 (15.0-32.0) | 25.0 (15.0-35.0) |
| Final diagnosis | |||
| Benign condition | 90 (74.4) | 95 (79.2) | 185 (76.8) |
| Malignant condition | 31 (25.6) | 25 (20.8) | 56 (23.2) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); IQR, interquartile range.
SI conversion factor: To convert calcium to mmol/L, multiply by 0.25; to convert parathyroid hormone to ng/L, multiply by 1.