Table 2. Primary and Secondary Outcomes.
Characteristic | No. (%) [95% CI] | P Value | |
---|---|---|---|
Near Infrared–Induced Autofluorescence (n = 121) | Standard Care (n = 120) | ||
Primary outcome | |||
Postoperative hypocalcemia at postoperative day 1 or 2 | 11 (9.1) [4.0-14.2] | 26 (21.7) [14.3-29.0] | .007a |
Secondary outcomes | |||
Nadir of postoperative corrected calcium, median (IQR), mg/dL | 8.86 (8.62-9.18) | 8.74 (8.25-9.03) | .025b |
Parathyroid hormone at postoperative day 1, median (IQR), pg/mL | 33.2 (21.9-48.1) | 28.6 (12.0-46.5) | .07b |
Supplementation | |||
Calcium only | 11 (9.1) [4.0-14.2] | 24 (20.0) [12.8-27.2] | .016a |
Calcium and vitamin D | 6 (5.0) [1.1-8.9] | 8 (6.7) [2.9-12.8] | .78c |
Identified parathyroid glands, No. | |||
0 | 1 (0.8) [0.0-2.5] | 2 (1.7) [0.0-4.0] | <.001a |
1 | 2 (1.7) [0.0-4] | 19 (15.8) [9.3-22.4] | |
2 | 20 (16.5) [10.0-23.3] | 40 (33.3) [24.9-41.8] | |
3 | 40 (33.1) [24.9-41.8] | 36 (30.0) [21.8-38.2] | |
4 | 57 (47.1) [38.5-56.4] | 23 (19.2) [12.1-26.2] | |
Not determined | 1 (0.8) [0-2.5] | NA | |
Inadvertently resected parathyroid glands, No. | 3 (2.5) [0-5.2] | 14 (11.7) [5.9-17.4] | .006c |
Autotransplanted parathyroid glands, No. | |||
0 | 116 (95.9) [93.5-99.9] | 104 (86.7) [80.6-92.8] | .009a |
≥1 | 4 (3.3) [0.1-6.6] | 16 (13.3) [7.3-19.4] | |
Not determined | 1 (0.8) [0.0-2.5] | ||
Permanent hypocalcemia | 0 | 2 (1.7) [0.0-4.0] | .15c |
Nonparathyroid complication | 3 (2.5) [0.0-5.3] | 3 (2.5) [0.0-5.3] | >.99c |
Duration of hospitalization, median (IQR), d | 3 (3.0-4.0) | 3.0 (3.0-4.0) | .98b |
Abbreviations: IQR, interquartile range; NA, not applicable.
SI conversion factor: To convert calcium to mmol/L, multiply by 0.25; to convert parathyroid hormone to ng/L, multiply by 1.
χ2 Test applied.
Wilcoxon test applied.
Fisher test applied.