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. 2019 Nov 6;155(2):106–112. doi: 10.1001/jamasurg.2019.4613

Table 2. Primary and Secondary Outcomes.

Characteristic No. (%) [95% CI] P Value
Near Infrared–Induced Autofluorescence (n = 121) Standard Care (n = 120)
Primary outcome
Postoperative hypocalcemia at postoperative day 1 or 2 11 (9.1) [4.0-14.2] 26 (21.7) [14.3-29.0] .007a
Secondary outcomes
Nadir of postoperative corrected calcium, median (IQR), mg/dL 8.86 (8.62-9.18) 8.74 (8.25-9.03) .025b
Parathyroid hormone at postoperative day 1, median (IQR), pg/mL 33.2 (21.9-48.1) 28.6 (12.0-46.5) .07b
Supplementation
Calcium only 11 (9.1) [4.0-14.2] 24 (20.0) [12.8-27.2] .016a
Calcium and vitamin D 6 (5.0) [1.1-8.9] 8 (6.7) [2.9-12.8] .78c
Identified parathyroid glands, No.
0 1 (0.8) [0.0-2.5] 2 (1.7) [0.0-4.0] <.001a
1 2 (1.7) [0.0-4] 19 (15.8) [9.3-22.4]
2 20 (16.5) [10.0-23.3] 40 (33.3) [24.9-41.8]
3 40 (33.1) [24.9-41.8] 36 (30.0) [21.8-38.2]
4 57 (47.1) [38.5-56.4] 23 (19.2) [12.1-26.2]
Not determined 1 (0.8) [0-2.5] NA
Inadvertently resected parathyroid glands, No. 3 (2.5) [0-5.2] 14 (11.7) [5.9-17.4] .006c
Autotransplanted parathyroid glands, No.
0 116 (95.9) [93.5-99.9] 104 (86.7) [80.6-92.8] .009a
≥1 4 (3.3) [0.1-6.6] 16 (13.3) [7.3-19.4]
Not determined 1 (0.8) [0.0-2.5]
Permanent hypocalcemia 0 2 (1.7) [0.0-4.0] .15c
Nonparathyroid complication 3 (2.5) [0.0-5.3] 3 (2.5) [0.0-5.3] >.99c
Duration of hospitalization, median (IQR), d 3 (3.0-4.0) 3.0 (3.0-4.0) .98b

Abbreviations: IQR, interquartile range; NA, not applicable.

SI conversion factor: To convert calcium to mmol/L, multiply by 0.25; to convert parathyroid hormone to ng/L, multiply by 1.

a

χ2 Test applied.

b

Wilcoxon test applied.

c

Fisher test applied.