Figure 5.

Most minor intron-containing genes (MIGs) are expressed stably during cell cycle. Data plotted for (A) 624 protein-coding MIGs, (B) 28 core essentialome MIGs, and (C) 63 majority essentialome MIGs deemed to be expressed during cell cycle (as determined by TPM≥1 in at least one stage of cell cycle). Data obtained from analysis of RNAseq generated by Singh et al. (2013). Each line represents the expression of one MIG throughout successive stages of cell cycle (early G1, late G1, S, and G2/M). Colored lines indicate MIGs that showed differential expression in at least one stage of cell cycle relative to the previous stage, gray lines are MIGs that are non-differentially expressed (NonDE) in all stages, and dashed lines represent MIGs in the younger essentialome.