There was no interaction observed between whether a patient had ever filled a non–P2Y12 inhibitor secondary prevention medication at the same time as a P2Y12 inhibitor and the observed association with persistence (A) or adherence (B) in taking other cardiovascular medications. Variables for adjustment included hospital characteristics, demographic information, comorbidities, details of the index presentation and hospital course, and patient responses to baseline survey questions about quality of life and medication-taking behaviors. ACE indicates antiotengin-converting enzyme; ARB, angiotension II–receptor blocker.