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. 2019 Oct 23;8(11):1493–1502. doi: 10.1530/EC-19-0379

Table 3.

Correlation analysis between individual islet autoantibody and clinical features.

GADA positive (n = 41) IAA positive (n = 103) ICA positive (n = 15)
Age (years)
r −0.018 0.020 0.042
P 0.700 0.666 0.354
Gender (male/female)
r −0.038 −0.029 0.047
 P 0.404 0.531 0.307
BMI (kg/m2)
r −0.167 0.009 0.025
P <0.0001a 0.841 0.583
WHR
r −0.103 0.016 0.055
P 0.021b 0.715 0.222
Duration of diabetes (years)
r 0.002 0.029 −0.118
P 0.965 0.516 0.329
Insulin treatment
r 0.051 0.283 −0.026
P 0.268 <0.0001a 0.569
Diabetic family history
r −0.006 0.012 0.010
P 0.888 0.785 0.820
FBG (mmol/L)
r 0.065 0.094 −0.036
P 0.146 0.038b 0.428
HbA1C (%)
r 0.049 0.040 −0.007
P 0.285 0.390 0.876
LDL-CH (mmol/L)
r −0.040 −0.004 0.010
P 0.378 0.379 0.824
HDL-CH (mmol/L)
r 0.033 0.185 −0.020
P 0.470 <0.0001a 0.652
TG (mmol/L)
r −0.111 −0.046 −0.012
P 0.014b 0.309 0.788
TCHOL (mmol/L)
r −0.053 0.062 0.011
P 0.238 0.171 0.812
ALT (U/L)
r 0.070 0.047 −0.089
P 0.118 0.295 0.202
AST (U/L)
r −0.020 0.093 −0.019
P 0.656 0.039b 0.668
AST/ALT
r 0.002 0.035 0.079
P 0.967 0.431 0.078
GGT (U/L)
r −0.057 0.049 0.030
P 0.209 0.047b 0.510
Ucr (μmol/L)
r −0.082 −0.059 −0.071
P 0.074 0.199 0.124
UREA (mmol/L)
r 0.074 0.023 0.016
P 0.100 0.603 0.727
mALB (mg/L)
r −0.122 −0.051 0.024
P 0.007c 0.262 0.605
U-mALB/Ucr (mg/g)
r −0.090 0.002 0.024
P 0.052 0.959 0.605
CREA (μmol/L)
r −0.045 0.001 0.078
P 0.323 0.974 0.683
UA (μmol/L)
r −0.085 −0.062 0.056
P 0.059 0.168 0.210

Data of r and P values were calculated from Spearman correlation analysis. A P value <0.05 was considered as statistically significant. Significant correlations were in bold and the significance level is indicated with superscript letters.

aP < 0.0001, bP < 0.05 and cP < 0.01.

ALT, alanine aminotransferase; AST, aspartate transaminase; BMI, body mass index; CREA, serum creatinine; FBG, fasting blood glucose; GADA, glutamic acid decarboxylase autoantibodies; GGT, γ-glutamyltransferase; HbA1c, hemoglobin A1c; HDL-CH, high-density lipoprotein (cholesterol); IAA, insulin autoantibodies; ICA, islet cell cytoplasmic autoantibodies; LDL-CH, low-density lipoprotein (cholesterol); mALB, urinary microalbumin; TCHOL, total cholesterol; TG, triglycerides; UA, serum uric acid; Ucr, urine creatinine; WHR, waist-hip ratio.