Table 4.
Independent factors related to autoantibody positivity by unconditional logistic regression analysis.
| OR (95% CI) | P value | |
|---|---|---|
| GADA | ||
| Age (years) | 1.00 (0.95–1.05) | 0.945 |
| Gender | 1.03 (0.49–2.20) | 0.931 |
| BMI (kg/m2) | 0.59 (0.27–1.30) | 0.190 |
| WHR | 0.40 (0.17–0.95) | 0.037a |
| TG (mmol/L) | 0.36 (0.17–0.79) | 0.010a |
| Ucr (μmol/L) | 1.00 (0.997–1.003) | 0.930 |
| mALB (mg/L) | 0.36 (0.17–0.79) | 0.011a |
| UA (μmol/L) | 0.64 (0.30–1.36) | 0.244 |
| IAA | ||
| Age (years) | 1.01 (0.97–1.04) | 0.713 |
| Gender | 0.94 (0.57–1.55) | 0.807 |
| BMI (kg/m2) | 1.19 (0.73–1.95) | 0.492 |
| Insulin treatment | 18.9 (8.49–42.2) | <0.0001b |
| FBG (mmol/L) | 4.13 (2.15–7.94) | <0.001c |
| HDL-CH (mmol/L) | 2.30 (1.34–3.96) | 0.003d |
| AST (U/L) | 1.64 (1.00–2.69) | 0.050a |
| GGT (U/L) | 1.51 (1.00–2.28) | 0.052 |
| ICA | ||
| Age (years) | 1.00 (0.93–1.09) | 0.914 |
| Gender | 1.82 (0.62–5.37) | 0.277 |
| BMI (kg/m2) | 0.75 (0.26–2.26) | 0.608 |
| AST/ALT | 2.51 (0.77–8.15) | 0.125 |
OR (95% CI) and P value were calculated by unconditional logistic regression and P value ≤0.05 were considered statistically significant. Significant correlations were in bold and the significance level is indicated with superscript letters.
aP ≤ 0.05, bP < 0.0001, cP < 0.001, dP < 0.01.
AST, aspartate transaminase; BMI, body mass index; CI, confidence interval; FBG, fasting blood glucose; GADA, glutamic acid decarboxylase autoantibodies; GGT, γ-glutamyltransferase; HDL-CH, high-density lipoprotein (cholesterol); IAA, insulin autoantibodies; ICA, islet cell cytoplasmic autoantibodies; mALB, Urinary microalbumin; OR, odds ratio; TG, triglycerides; UA, serum uric acid; Ucr, urine creatinine; WHR, waist-hip ratio.
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