Figure 3.

Indices of bone formation consisting of osteoblast perimeter (A), mineralizing perimeter (B), mineral apposition rate (C), bone formation rate/bone perimeter (D), bone formation rate/bone area (E), bone formation rate/tissue area (F), serum osteocalcin, and indices of bone resorption consisting of osteoclast perimeter (H) and serum CTX-1 in male B6 mice maintained at 22°C and 32°C from 5 to 16 weeks of age. Representative histological images of the distal femur metaphysis (J) illustrating differences in fluorochrome labeling with temperature. Data are mean ± s.e. ^aDifferent from mice housed at 22°C, P < 0.05; n = 9–10/group.