Table 5.

Regions in which seed‐based resting functional connectivity strengths were significantly different across pediatric (acute and chronic) and adult (chronic) groups, as compared with healthy controls

	X	Y	Z	t‐statistic value	Cluster size	p‐value
Pediatric acute > controls
Orbitofrontal cortex “seed”
Right hippocampus	28	−28	−16	4.84
	24	−26	−16	4.80	152	.013
	16	−32	−20	3.95
Pediatric chronic < controls
Ventral posterolateral nucleus “seed”
Bilateral primary motor cortex/primary somatosensory cortex	2	−18	60	6.39
	0	−32	62	4.74	254	.0001
	−4	−22	68	3.93
Adult chronic > controls
Anterior cingulate cortex “seed”
Left primary somatosensory cortex	−50	−24	62	5.46
	−36	−26	66	4.61	93	.048
	−34	−30	62	4.38
Adult chronic < controls
Ventral posterolateral nucleus “seed”
Bilateral posterior cingulate cortex	−2	−30	44	4.30
	0	−24	38	4.00	137	.023
	6	−14	34	3.75

Note: “seed” clusters were derived from the previous pediatric and adult gray matter density analyses. Locations are in Montreal Neurological Institute space. Significant clusters were from cluster‐extent thresholding (family‐wise error rate) to correct for multiple comparisons.