Table 3.

Results of the whole‐brain VBM analysis comparing GMV between groups (MetS: n = 104 vs. metabolically healthy control: n = 104

Metabolic syndrome VBM contrast analysis (n = 208)
Cluster	Cluster size (voxels)	Foci: MNI coordinates			Max t‐score within cluster	Cluster foci: MNI Daemon label
		x	y	z
Brainstem	13,187	2	−28	−48	4.98	Pons
L. Cerebellum	28,818	−24	−62	−46	5.73	L. Crus I
		−44	−46	−30	3.62	L. Culmen
R. Cerebellum	24,419	20	−66	−46	5.44	R. Cerebellar tonsil
Orbitofrontal cortex	9,175	4	14	−24	5.66	R. Rectal gyrus (BA11)
		12	62	−22	3.90	R. Superior Frontal Gyrus (BA10)
		12	44	−28	4.14	R. Medial frontal gyrus (BA11)
		−6	14	−28	4.68	L. Rectal gyrus
		−12	34	−32	3.64	L. Orbital gyrus (BA47)
		−2	28	−30	4.49	L. Rectal gyrus (BA11)
L. Limbic lobe	891	−16	−28	−12	3.00	L. Parahippocampal gyrus
R. Limbic lobe	3,071	18	2	−18	4.25	Subcallosal gyrus (BA34)
		27	−2	−16	3.60	R. Amygdala
R. insula	4,026	34	0	−12	3.73	R. Claustrum
		42	−2	−8	3.41	R. Insula
L. Caudate	2,752	−12	16	10	4.70	L. Caudate body
R. Caudate	4,054	8	22	8	4.59	R. Caudate body
		6	14	4	4.00	R. Caudate body
Cuneus	2,787	−4	−64	8	3.51	L. Cuneus
		−6	−84	8	3.05	L. Lingual gyrus
R. Temporal lobe	2,444	70	−24	0	4.15	R. Superior temporal gyrus (BA22)
		68	−12	−6	3.33	R. Middle temporal gyrus
Lingual gyrus	637	8	−98	4	3.19	R. Lingual gyrus

Results are significant at FWE p < .05, corrected for multiple comparisons at the voxel level.

Abbreviations: BA, Brodmann area; L., left; R., right.