Table II.
Multivariate survival analyses of stage and CDK9 with overall survival of patients with COAD using the Cox proportional hazards model.
| Factor | Coefficient | HR | 95% CI_l | 95% CI_u | P-value |
|---|---|---|---|---|---|
| Stage II | 0.646 | 1.908 | 0.737 | 4.941 | 0.183 |
| Stage III | 1.166 | 3.208 | 1.243 | 8.277 | 0.016a |
| Stage IV | 2.241 | 9.406 | 3.629 | 24.381 | 0.000b |
| CDK9 | 0.625 | 1.868 | 1.151 | 3.033 | 0.011a |
Model: Survival (COAD) ~ Stage + CDK9. Data from a total of 445 patients were analysed, including 98 cases of mortality. Data was obtained from the TIMER database. The coefficient reads as a regression coefficient. HR, and its lower and upper 95% CI are shown.
a
P<0.05
b
P<0.001. 95% CI-l, lower 95% CI; 95% CI-u, upper 95% CI; CDK9, cyclin dependent kinase 9; COAD, colon adenocarcinoma; HR, hazard ratio.