Table III.
Multivariate survival analyses of stage and CDK9 with overall survival of patients with READ using the Cox proportional hazards model.
| Factor | Coefficient | HR | 95% CI_l | 95% CI_u | P-value |
|---|---|---|---|---|---|
| Stage II | 0.156 | 1.169 | 0.225 | 6.090 | 0.853 |
| Stage III | 0.726 | 2.066 | 0.426 | 10.026 | 0.368 |
| Stage IV | 1.657 | 5.244 | 1.104 | 24.907 | 0.037a |
| CDK9 | 0.823 | 2.277 | 0.775 | 6.696 | 0.135 |
Model: Survival (READ) ~ Stage + CDK9. Data from a total of 160 patients were analysed, including 23 cases of mortality. Data was obtained from TIMER database. The coefficient reads as a regression coefficient. HR, and its lower and upper 95% confidential interval are shown.
a
P<0.05. 95% CI_l, lower 95% CI; 95% CI_u, upper 95% CI; CDK9, cyclin dependent kinase 9; HR, hazard ratio; READ, rectum adenocarcinoma.