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. 2019 Oct 8;18(6):6228–6236. doi: 10.3892/ol.2019.10968

Figure 2.

Figure 2.

Propofol reduces miR-10b expression and increases HOXD10 levels in bladder cancer cells. (A) The relative expression levels of miR-10b in bladder cancer T24 cells following 48-h 10 µg/ml propofol treatment were detected by reverse transcription-quantitative PCR. Propofol treatment significantly reduced miR-10b expression levels in T24 cells. U6 was used as an internal control. Treatment of T24 cells with 10 µg/ml propofol significantly increased the (B) mRNA and (C) protein expression of HOXD10. GAPDH was used as an internal control. *P<0.05. Propofol, 2,6-diisopropylphenol; HOXD10, homeobox D10; U6, U6 small nuclear RNA; miR, microRNA.