Table 4.
Condition differences of DCM connectivity strength within group. Significant differences are marked with a star, threshold of significance considered at Pp > 0.95 corresponding to 5% of chance of false discovery rate (Pp = posterior probability). UNIP and BIP correspond to values of modulatory connectivity (B parameter of the DCM matrix) specific to each condition. Effect size corresponds to Cohen's d ([M2–M1]/SD pooled), where M1 and M2 are the average value for each group or condition, and SD pooled = √([SD 1 2 + SD 2 2]/2)
| SMA proper left → M1 left | SMA proper left → M1 right | SMA proper left → SMA proper right | M1 left → M1 right | |
|---|---|---|---|---|
| HV | ||||
| UNIP | −0.24 ± 0.10 | −0.57 ± 0.10 | −0.41 ± 0.09 | −0.59 ± 0.11 |
| BIP | −0.17 ± 0.14 | 0.03 ± 0.14 | 0.01 ± 0.11 | 0.32 ± 0.12 |
| Pp (effect size) | 0.66 | 0.99* (−4.93) | 0.99* (−4.18) | 0.95* (−7.91) |
| CMM | ||||
| UNIP | 0.04 ± 0.10 | −0.51 ± 0.11 | −0.11 ± 0.11 | 0.25 ± 0.11 |
| BIP | −0.48 ± 0.15 | 0.21 ± 0.14 | −0.13 ± 0.12 | −0.40 ± 0.12 |
| Pp (effect size) | 0.99* (−4.08) | 1* (−5.72) | 0.57 | 1* (−5.65) |
CMM: patients with congenital mirror movements; DCM = dynamic causal modeling; HVs = healthy volunteers; SMA = supplementary motor area; UNIP = unimanual preparation.