Table A2.
MNI coordinates, cluster extent, and statistical values of significant clusters from the DBM analysis described in Figure 1
| Set level | Cluster level | Peak level | MNI coordinates (mm) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Contrast | p | c | p FWE | q FDR | K E | p uncorr | p FWE | q FDR | T | p uncorr | x | y | z |
| C+: t1 − t2 | .000 | 3 | .000 | .000 | 6,554 | .000 | .000 | .001 | 6.23 | .000 | 4.5 | 54 | 18 |
| .002 | .011 | 5.58 | .000 | ‐3 | 60 | −6 | |||||||
| .003 | .013 | 5.44 | .000 | −3 | 51 | 19.5 | |||||||
| .000 | .000 | 5,380 | .000 | .013 | .023 | 5.12 | .000 | 1.5 | 16.5 | 13.5 | |||
| .021 | .024 | 4.99 | .000 | 7.5 | 4.5 | 4.5 | |||||||
| .079 | .063 | 4.64 | .000 | −9 | 21 | 9 | |||||||
| .013 | .025 | 1,102 | .002 | .068 | .058 | 4.68 | .000 | 3 | −63 | 48 | |||
| .590 | .329 | 3.92 | .000 | 7.5 | −72 | 43.5 | |||||||
| C+: t2 − t1 | .000 | 4 | .023 | .019 | 956 | .003 | .007 | .041 | 5.26 | .000 | −13.5 | −49.5 | −34.5 |
| .532 | .282 | 3.97 | .000 | −16.5 | −34.5 | −37.5 | |||||||
| .000 | .000 | 5,928 | .000 | .110 | .142 | 4.54 | .000 | 27 | −66 | 19.5 | |||
| .185 | .142 | 4.38 | .000 | 28.5 | −58.5 | −3 | |||||||
| .225 | .142 | 4.31 | .000 | 13.5 | −78 | −7.5 | |||||||
| .000 | .000 | 5,267 | .000 | .133 | .142 | 4.48 | .000 | −22.5 | 9 | 37.5 | |||
| .200 | .142 | 4.35 | .000 | −27 | 1.5 | 15 | |||||||
| .259 | .144 | 4.26 | .000 | −22.5 | 9 | −7.5 | |||||||
| .007 | .008 | 1,269 | .001 | .234 | .142 | 4.30 | .000 | 25.5 | 10.5 | 15 | |||
| .267 | .144 | 4.25 | .000 | 22.5 | 4.5 | −6 | |||||||
| .769 | .436 | 3.76 | .000 | 22.5 | 19.5 | 1.5 | |||||||
| C−: t1 − t2 | .000 | 5 | .000 | .000 | 27,444 | .000 | .001 | .021 | 5.76 | .000 | −34.5 | −48 | −36 |
| .003 | .022 | 5.46 | .000 | −16.5 | 19.5 | 18 | |||||||
| .010 | .048 | 5.18 | .000 | −24 | −70.5 | −36 | |||||||
| .000 | .000 | 2,972 | .000 | .004 | .022 | 5.43 | .000 | 9 | 73.5 | 4.5 | |||
| .027 | .075 | 4.93 | .000 | 6 | 51 | 3 | |||||||
| .063 | .116 | 4.70 | .000 | −4.5 | 55.5 | 1.5 | |||||||
| .000 | .001 | 2,125 | .000 | .023 | .075 | 4.97 | .000 | 48 | 24 | −1.5 | |||
| .092 | .130 | 4.59 | .000 | 34.5 | 22.5 | 0 | |||||||
| .198 | .157 | 4.35 | .000 | 51 | −37.5 | 9 | |||||||
| .017 | .025 | 1,033 | .002 | .058 | .114 | 4.72 | .000 | 7.5 | −72 | 13.5 | |||
| .382 | .205 | 4.12 | .000 | 9 | 57 | 18 | |||||||
| .536 | .272 | 3.97 | .000 | 13.5 | −91.5 | 3 | |||||||
| .010 | .019 | 1,171 | .001 | .568 | .280 | 3.94 | .000 | 22.5 | −10.5 | 21 | |||
| .626 | .294 | 3.89 | .000 | 18 | 3 | 18 | |||||||
| .967 | .663 | 3.45 | .000 | 22.5 | −4.5 | 28.5 | |||||||
| C−: t2 − t1 | .067 | 1 | .001 | .001 | 1,920 | .000 | .003 | .004 | 5.46 | .000 | −3 | −33 | 52.5 |
Statistics are performed at three levels: Set level (indicating chance of finding this number of clusters), cluster level, and peak level. Significance in this study was assessed on cluster level for a Bonferroni‐correct p < .05.
Abbreviations: c, number of clusters found at p < .001; C−, patients with breast cancer who did not undergo chemotherapy; C+, patients breast cancer who underwent chemotherapy; HC, healthy controls; K E, Cluster extent (in voxels); p FWE, Bonferroni corrected p; q FDR, false‐discovery rate corrected q; t1, timepoint 1; t2, timepoint 2.