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. 2019 Oct 11;18(6):6117–6125. doi: 10.3892/ol.2019.10980

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Shi reverses the influence of overexpressed YAP in HCT116 and SW620 cells. MTT assay was used to detect the effect of YAP overexpression in combination with 10 µM Shi on (A) HCT116 and (B) SW620 cell growth. YAP, LC3-II and p62 expression levels were determined using western blot analysis in (C) HCT116 and (D) SW620 cells transfected with YAP cDNA or treated with Shi. (E-H) Densitometry analysis of LC3-II, p62 and YAP. *P<0.05 compared with control. ^#P<0.05, compared with YAP cDNA transfection. Shi, shikonin; YAP, yes-associated protein.