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. 2019 Oct 8;18(6):6275–6283. doi: 10.3892/ol.2019.10966

Table I.

Treatment strategy.

NLR, n (%) PLR, n (%) MLR, n (%)



Treatment All groups (n=436) NLR≤2.65 (n=346) NLR>2.65 (n=90) P-value PLR ≤190.9 (n=382) PLR >190.9 (n=54) P-value MLR ≤0.28 (n=275) MLR>0.28 (n=159) P-value
Chemotherapy 0.0498 0.088 0.627
  No 45 (10) 41 (12) 4 (4) 43 (11) 2 (4) 30 (11) 15 (9)
  Yes 391 (90) 305 (88) 86 (96) 339 (89) 52 (96) 245 (89) 144 (91)
Chemotherapy regimen
  Total n for all chemotherapy patients 391 305 86 339 52 245 144
  AC FAC 302 (77) 241 (79) 61 (71) 0.025 265 (78) 37 (71) 0.026 193 (79) 108 (75) 0.441
  AC + taxanes 80 (20) 56 (18) 24 (28) 66 (19) 14 (27) 47 (19) 33 (23)
  CMF 8 (2) 8 (3) 0 8 (2) 0 5 (2) 2 (1)
  Other 1 (0) 0 1 (1) 0 1 (2) 0 1 (1)
Local treatment 0.042 0.0001 0.153
  Mastectomy 278 (64) 224 (65) 54 (60) 246 (64) 32 (59) 177 (64) 99 (62)
  Breast conservation surgery 130 (30) 105 (30) 25 (28) 119 (31) 11 (20) 85 (31) 45 (28)
  Without surgery 28 (6) 17 (5) 11 (12) 17 (4) 11 (20) 13 (5) 15 (9)
Hormonotherapy 0.015 0.006 0.012
  No 149 (34) 108 (31) 41 (46) 121 (32) 28 (52) 82 (30) 67 (42)
  Yes 287 (66) 238 (69) 49 (54) 261 (68) 26 (48) 193 (70) 92 (58)
Radiotherapy 0.981 0.359 0.225
  No 111 (25) 88 (25) 23 (26) 100 (26) 11 (20) 75 (27) 35 (22)
  Yes 325 (75) 258 (75) 67 (74) 282 (74) 43 (80) 200 (73) 124 (78)

Data are presented as n (%). AC, Adriamycin (or doxorubicin; 60 mg/m2) and Cyclophosphamide (600 mg/m2) treatment; FAC, Fluorouracil (500 mg/m2), Adriamycin (or doxorubicin; 50 mg/m2) and Cyclophosphamide (500 mg/m2) treatment; CMF, Cyclophosphamide (100 mg/m2), Methotrexate (40 mg/m2) and Fluorouracil (600 mg/m2) treatment.