Table 2.

Differentiation of patients with PSP from patients with PD using TDI

Classification analysis at whole‐brain level
	AUC	Specificity (%)	Sensitivity (%)	PPV (%)	NPV (%)
HC vs. PSP‐RS	0.87	87	75	83	80
PD vs. PSP‐RS	0.82	86	60	80	69
HC vs. PD	0.45	56	38	44	50

Classification analysis considering the superior cerebellar peduncles
	AUC	Specificity (%)	Sensitivity (%)	PPV (%)	NPV (%)
HC vs. PSP‐RS	1	100	95	100	96
PD vs. PSP‐RS	0.98	100	90	100	91

AUC = area under the curve; PPV = positive predictive value; NPV = negative predictive value; PD = Parkinson's disease patients; PSP‐RS = Progressive Supranuclear Palsy patients (Richardson's syndrome); HC = healthy controls.

In the upper side: Classification analysis was performed at whole‐brain level; in the lower side: Classification analysis was performed using the voxels that belong to the superior cerebellar peduncle.