Figure 2.

Regulatory factors of ARC. The factors that can either enhance ARC expression or prevent its degradation, are presented in green. The factors that can either inhibit ARC expression levels or promote its degradation, are presented in pink. The phosphorylation reaction of ARC regulated by CK2 are presented in lilac. ARC, apoptosis repressor with caspase recruitment domain; Ras, Rat sarcoma; FOXO3A, Fork head box O3; I/R, Ischemia/Reperfusion; SNX13, Sorting Nexin 13; p53, protein 53 or tumor protein 53; CK2, casein kinase 2; P, phosphorylation.