Table 2.
Results for the global network
| Correlation threshold | Metric | Healthy controls | ET patients | p value |
|---|---|---|---|---|
| 0.01 | GE | 0.786 ± 0.020 | 0.796 ± 0.022 | .043 a |
| LE | 0.837 ± 0.018 | 0.845 ± 0.019 | .063 | |
| BC | 0.003 ± 0.000 | 0.003 ± 0.000 | .043 b | |
| Cost | 0.571 ± 0.041 | 0.592 ± 0.044 | .043 a | |
| APL | 1.429 ± 0.041 | 1.408 ± 0.044 | .043 b | |
| CC | 0.675 ± 0.036 | 0.690 ± 0.039 | .063 | |
| Degree | 93.111 ± 6.655 | 96.461 ± 7.216 | .043 a | |
| 0.03 | GE | 0.769 ± 0.021 | 0.779 ± 0.022 | .048 a |
| LE | 0.828 ± 0.018 | 0.835 ± 0.020 | .074 | |
| BC | 0.003 ± 0.000 | 0.003 ± 0.000 | .048 b | |
| Cost | 0.538 ± 0.042 | 0.558 ± 0.045 | .048 a | |
| APL | 1.462 ± 0.042 | 1.442 ± 0.045 | .048 b | |
| CC | 0.655 ± 0.037 | 0.671 ± 0.040 | .074 | |
| Degree | 87.661 ± 6.810 | 91.009 ± 7.318 | .048 a | |
| 0.05 | GE | 0.752 ± 0.021 | 0.762 ± 0.023 | .059 |
| LE | 0.819 ± 0.018 | 0.826 ± 0.020 | .092 | |
| BC | 0.003 ± 0.000 | 0.003 ± 0.000 | .059 | |
| Cost | 0.505 ± 0.042 | 0.524 ± 0.046 | .060 | |
| APL | 1.496 ± 0.042 | 1.476 ± 0.046 | .059 | |
| CC | 0.637 ± 0.037 | 0.652 ± 0.041 | .092 | |
| Degree | 82.242 ± 6.840 | 85.452 ± 7.496 | .060 | |
| 0.07 | GE | 0.736 ± 0.021 | 0.745 ± 0.024 | .070 |
| LE | 0.810 ± 0.019 | 0.817 ± 0.021 | .107 | |
| BC | 0.003 ± 0.000 | 0.003 ± 0.000 | .071 | |
| Cost | 0.471 ± 0.042 | 0.490 ± 0.047 | .070 | |
| APL | 1.529 ± 0.042 | 1.510 ± 0.047 | .071 | |
| CC | 0.620 ± 0.038 | 0.634 ± 0.042 | .108 | |
| Degree | 76.827 ± 6.894 | 79.933 ± 7.664 | .070 | |
| 0.09 | GE | 0.719 ± 0.021 | 0.728 ± 0.024 | .075 |
| LE | 0.802 ± 0.020 | 0.808 ± 0.021 | .120 | |
| BC | 0.003 ± 0.000 | 0.003 ± 0.000 | .075 | |
| Cost | 0.438 ± 0.042 | 0.457 ± 0.047 | .075 | |
| APL | 1.562 ± 0.043 | 1.544 ± 0.047 | .075 | |
| CC | 0.603 ± 0.039 | 0.616 ± 0.043 | .121 | |
| Degree | 71.466 ± 6.897 | 74.518 ± 7.685 | .075 | |
| 0.11 | GE | 0.703 ± 0.021 | 0.711 ± 0.023 | .100 |
| LE | 0.794 ± 0.020 | 0.800 ± 0.022 | .133 | |
| BC | 0.004 ± 0.000 | 0.004 ± 0.000 | .103 | |
| Cost | 0.407 ± 0.043 | 0.424 ± 0.047 | .099 | |
| APL | 1.595 ± 0.043 | 1.578 ± 0.047 | .103 | |
| CC | 0.588 ± 0.040 | 0.601 ± 0.044 | .135 | |
| Degree | 66.283 ± 6.977 | 69.049 ± 7.636 | .099 | |
| 0.13 | GE | 0.687 ± 0.022 | 0.695 ± 0.024 | .110 |
| LE | 0.786 ± 0.021 | 0.792 ± 0.023 | .150 | |
| BC | 0.004 ± 0.000 | 0.004 ± 0.000 | .109 | |
| Cost | 0.375 ± 0.043 | 0.392 ± 0.047 | .110 | |
| APL | 1.630 ± 0.045 | 1.613 ± 0.048 | .109 | |
| CC | 0.574 ± 0.041 | 0.586 ± 0.045 | .152 | |
| Degree | 61.172 ± 7.042 | 63.837 ± 7.667 | .110 | |
| 0.15 | GE | 0.671 ± 0.022 | 0.679 ± 0.024 | .118 |
| LE | 0.779 ± 0.021 | 0.785 ± 0.023 | .152 | |
| BC | 0.004 ± 0.000 | 0.004 ± 0.000 | .116 | |
| Cost | 0.345 ± 0.042 | 0.361 ± 0.047 | .120 | |
| APL | 1.667 ± 0.046 | 1.649 ± 0.050 | .116 | |
| CC | 0.560 ± 0.041 | 0.573 ± 0.046 | .156 | |
| Degree | 56.242 ± 6.849 | 58.827 ± 7.684 | .120 | |
| 0.17 | GE | 0.654 ± 0.022 | 0.662 ± 0.024 | .127 |
| LE | 0.772 ± 0.021 | 0.778 ± 0.024 | .161 | |
| BC | 0.004 ± 0.000 | 0.004 ± 0.000 | .119 | |
| Cost | 0.316 ± 0.041 | 0.331 ± 0.046 | .134 | |
| APL | 1.708 ± 0.049 | 1.690 ± 0.052 | .119 | |
| CC | 0.548 ± 0.041 | 0.560 ± 0.046 | .168 | |
| Degree | 51.548 ± 6.761 | 53.977 ± 7.555 | .134 |
Note. Values are expressed in means ± SD from the analysis of covariance. Every threshold follows the same contrast direction pattern. Significant values are in bold font.
Abbreviations: APL, average path length; BC, betweenness centrality; ET, Essential tremor; GE, global efficiency; LE, local efficiency.
ET patients > healthy controls.
Healthy controls > ET patients.