Table 3.

Regional graph topological analyses

ROI	Global efficiency		Local efficiency		Betweenness centrality		Cost		Average path length		Clustering coefficient		Degree
	L	R	L	R	L	R	L	R	L	R	L	R	L	R
Inferior frontal gyrus, pars opercularis	E>H						E>H		H>E				E>H
Middle temporal gyrus, posterior part	E>Ha						E>Ha		H>Ea				E>Ha
Inferior temporal gyrus, posterior division		E>H						E>H		H>E				E>H
Inferior temporal gyrus, temporo‐occipital part		E>H						E>H						E>H
Postcentral gyrus				E>Ha								E>Ha
Superior lateral occipital cortex			E>H							H>Eb	E>H
Inferior lateral occipital cortex		E>H						E>H		H>E				E>H
Intracalcarine cortex										H>E
Frontal medial cortex			E>H								E>H
Subcallosal cortex			E>H								E>H
Paracingulate gyrus	E>H						E>H		H>E				E>H
Posterior cingulate			E>H								E>H
Precuneus	E>H						E>H		H>E				E>H
Frontal orbital cortex									H>E
Parahippocampal gyrus, posterior division			E>H	E>H							E>H	E>H
Lingual gyrus	E>H			E>H			E>H		H>E			E>H	E>H
Frontal operculum					E>H
Planum polare						H>E
Pallidum										H>Eb
Hippocampus		E>H										E>H
Amygdala	E>H						E>H		H>E				E>H
Nucleus accumbens			E>H	E>H							E>H	E>H
Inferior semilunar lobule, caudal part				E>Ha		H>Ea						E>Ha
Biventral lobule, rostral part						H>Eb
Cerebellar tonsil						H>Eb
Flocculus				E>H								E>H
Culmen of vermis			E>Ha								E>Ha
Tuber of vermis					H>E

Note. E is the essential tremor patients and H is the healthy controls.

^aConsistent significance at a threshold of 0.15 and lower.

^bNot significant at lower thresholds.