Table 5.
Matrix of partial correlations among the cognitive domains and the ROIs that showed differences between ET patients versus healthy controls
ROI | Attention | Executive function | Verbal memory | Recognition | Visuospatial/visual functions | Language | Depressive symptoms | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
r | p value | r | p value | r | p value | r | p value | r | p value | r | p value | r | p value | |
Medial frontal cortex | ||||||||||||||
BC | −.476 | .022 | −.494 | .017 | ||||||||||
Right parahippocampal gyrus, posterior division | ||||||||||||||
LE | .563 | .005 | ||||||||||||
CC | −.431 | .045 | .577 | .004 | ||||||||||
Left parahippocampal gyrus, posterior division | ||||||||||||||
LE | −.473 | .023 | .441 | .035 | ||||||||||
BC | .483 | .019 | ||||||||||||
CC | −.475 | .022 | .428 | .042 | ||||||||||
Left lingual gyrus | ||||||||||||||
LE | −.435 | .038 | ||||||||||||
BC | .443 | .034 | .454 | .03 | ||||||||||
CC | −.435 | .038 | ||||||||||||
Right planum polare | ||||||||||||||
GE | .436 | .044 | .461 | .027 | ||||||||||
LE | .451 | .031 | ||||||||||||
Cost | .428 | .041 | .459 | .028 | ||||||||||
APL | −.445 | .033 | ||||||||||||
Degree | .428 | .041 | .459 | .028 | ||||||||||
CC | .422 | .045 | ||||||||||||
Right pallidum | ||||||||||||||
BC | .475 | .022 | ||||||||||||
Right hippocampus | ||||||||||||||
BC | −.504 | .014 | ||||||||||||
Right nucleus accumbens | ||||||||||||||
BC | .581 | .003 | .497 | .016 | .563 | .005 | .585 | .003 | ||||||
Right cerebellum flocculus | ||||||||||||||
LE | −.481 | .02 | ||||||||||||
CC | −.456 | .029 |
Abbreviations: APL, average path length; BC, betweenness centrality; ET, essential tremor; GE, global efficiency; LE, local efficiency; ROI, region of interest.