Figure 5.

Cumulative ranking of ROI performance across all measures of global cognition and function. For each measure of global cognition, [¹⁸F]AV1451 ROIs were ranked from worst to best (such that the worst region would have rank of 1) with respect to the effect size of the association between [¹⁸F]AV1451 in that region and the cognitive score. The ranks were then summed across all cognitive measurements and are displayed here. The data‐driven cluster 4 (“Temporo‐parietal”) ranked the best cumulatively across cognitive tests, with the data‐driven cluster 3 (“medial/inferior/anterior temporal”) ranking second best [Color figure can be viewed at http://wileyonlinelibrary.com]