Table 2.
Selected characteristics of the RTOG protocol 9003 study population with a PSS-HN (N=744)
| Age, median (IQR) | 60 | (53, 66) |
| Sex | No. of Patients | % of total |
| Male | 597 | 80.2 |
| Female | 147 | 19.8 |
| Race | ||
| White | 541 | 72.7 |
| Hispanic | 40 | 5.4 |
| Black | 145 | 19.5 |
| Other | 12 | 1.6 |
| Protocol RX | ||
| standard | 191 | 25.7 |
| HFX arm | 195 | 26.2 |
| AFX-C arm | 177 | 23.8 |
| AFX-S arm | 181 | 24.3 |
| Education | ||
| Grade 1-8, or none | 107 | 14.4 |
| Some high school | 180 | 24.2 |
| High school graduate | 211 | 28.4 |
| Some college/technical | 208 | 28.0 |
| Marital Status | ||
| Married | 370 | 49.7 |
| Not married | 356 | 47.8 |
| Smoking | ||
| Non-smoker | 72 | 9.7 |
| <20 pack years | 86 | 11.6 |
| 20-40 pack years | 180 | 24.2 |
| >40 pack years | 356 | 47.8 |
| Unknown, unanswered | 50 | 6.7 |
| Cancer site | ||
| Oral cavity | 76 | 10.2 |
| Oropharynx | 441 | 59.3 |
| Hypopharynx | 104 | 14.0 |
| Supraglottic larynx | 123 | 16.5 |
| KPS | ||
| 60 | 28 | 3.8 |
| 70 | 76 | 10.2 |
| 80 | 158 | 21.2 |
| 90 | 347 | 46.6 |
| 100 | 135 | 18.1 |
| Tumor classification | ||
| T1 | 43 | 5.8 |
| T2 | 202 | 27.2 |
| T3 | 277 | 37.2 |
| T4 | 222 | 29.8 |
| Lymph node classification | ||
| N0 | 158 | 21.2 |
| N1 | 150 | 20.2 |
| N2 | 349 | 46.9 |
| N3 | 87 | 11.7 |
| Highest grade toxicity within 6 months post-treatment | ||
| 0-2 | 328 | 44.1 |
| 3-5 | 416 | 55.9 |
Abbreviations: RTOG=radiation therapy oncology group, PSS-HN=Performance Status Scale for Head and Neck cancer patients, IQR=interquartile range, RX=radiation treatment, HFX=hyperfractionated, AFX-C=accelerated fractionated with concomitant boost, AFX-S=accelerated fractionated with a split