Table I.
Demographics and baseline characteristics of patients (n=95).
| Therapy group | |||
|---|---|---|---|
| Variable | DC-CIK alone | DC-CIK combined with CT | P-value |
| Cases, n | 45 | 50 | |
| Age (years; mean ± SD) | 61.2±8.1 | 60.8±9.3 | 0.753 |
| Sex | 0.805 | ||
| Female | 29 | 31 | |
| Male | 16 | 19 | |
| ECOG-PS | 0.402 | ||
| 0 | 29 | 28 | |
| 1 | 16 | 22 | |
| TNM staging | 0.297 | ||
| III | 10 | 7 | |
| IV | 35 | 43 | |
| Previous adjuvant chemotherapy | 0.858 | ||
| Yes | 17 | 18 | |
| No | 28 | 32 | |
| Histopathological type | 0.825 | ||
| Adenocarcinoma | 31 | 35 | |
| Squamous carcinoma | 14 | 15 | |
| T cell subtypes | |||
| Post/pre CD4+CD25+CD127+ T lymphocytes | 0.269 | ||
| >0.6 | 21 | 29 | |
| ≤0.6 | 24 | 21 | |
| Post/pre CD8+CD28+ T lymphocytes | 0.204 | ||
| >2.2 | 22 | 18 | |
| ≤2.2 | 23 | 32 | |
| Disease control | 0.001a | ||
| Stable | 10 | 28 | |
| Progressive | 35 | 22 | |
a
P<0.05. DC-CIK, dendritic cells mixed with cytokine-induced killer cells; CT, chemotherapy; TNM, Tumor-Node-Metastasis.