Ramberg 2009

Methods	Randomised, parallel group study. Patients and outcome assessors blind. One withdrawal due to reason unrelated to the trial from the Sodium Fluoride group.
Participants	Adults. Age 30 to 60 years. 60 enrolled, results given for 59.
Interventions	Brushing with a dentifrice containing 0.3% triclosan and 2.0% PVm/MA copolymer in a sodium fluoride silica base (Colgate® Total® Toothpaste, Colgate‐Palmolive Company, New York, NY, USA) versus brushing with a dentifrice containing 0.243 sodium fluoride in a silica base (Colgate® Cavity Protection® Toothpaste, Colgate‐Palmolive Company, New York, NY, USA). A soft‐bristled toothbrush was supplied. Study duration: 6 months.
Outcomes	PPD, BOP, plaque (presence/absence): data recorded at 3 and 6 months. 6 months data used.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"The subjects were randomly assigned to two treatment groups."
Allocation concealment (selection bias)	Low risk	"Personnel who did not take active part in the clinical examinations carried out the allocation of dentifrices according to the randomisation."
Blinding (performance bias and detection bias) All outcomes	Low risk	"The dentifrices were supplied in their original tubes, but over wrapped with a white label and coded so as to ensure that neither the examiner nor the participants were aware of the identity of the product."
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	No reply from author. One loss to follow‐up.
Selective reporting (reporting bias)	Unclear risk	No reply from author.
Other bias	Unclear risk	"This study was supported by the Colgate‐Palmolive Company".
Blinding of the patient?	Low risk	"The dentifrices were supplied in their original tubes, but over wrapped with a white label and coded so as to ensure that neither the examiner nor the participants were aware of the identity of the product."