Table 1.

Definitions of co-morbidities in children and adolescents, and cutoff points for defining remission and improvement

Co-morbidity	Test*	Remission	Improvement
T2DM	FPG, mmol/L	<7.0, and	7.0 preoperative level, and/or
	2-hr OGTT, mmol/L	<11.1, and	11.1 preoperative level, and/or
	HbA1c, %	< 6.5, and	6.5 preoperative level
Prediabetes	FPG, mmol/L	<5.6	5.6 preoperative level
	2-hr OGTT, mmol/L	<7.8	7.8 preoperative level
	HbA1c, %	<5.7	5.7 preoperative level
Dyslipidemia
LDL	LDL level, mmol/L	< 2.8	2.8 preoperative level
HDL	HDL level, mmol/L	>1.2	1.2 preoperative level
Cholesterol	Cholesterol level, mmol/L	<4.4	4.4 preoperative level
Triglycerides	Triglyceride level, mmol/L	Age 0–9 yr:
		<.8	.8 preoperative level
		Age 10–19 yr:
		<1.0	1.0 preoperative level
Hypertension	SBP	<95th percentile†	95th percentile† preoperative level, and/or
	DBP	<95th percentile†	95th percentile† preoperative level
Prehypertension	SBP	<90th percentile†	90th percentile† preoperative level, and/or
	DBP	<90th percentile†	90th percentile† preoperative level
OSA	Symptoms + AHI	Resolution of all symptoms	Improvement in symptom severity

OGTT = oral glucose tolerance test; AHI = apnea/hypopnea index, calculated from polysomnography; DBP = diastolic blood pressure; FPG = fasting plasma glucose; HbA_1c = glycated hemoglobin; HDL = high-density lipoprotein; LDL = low-density lipoprotein; OSA = obstructive sleep apnea; SBP = systolic blood pressure; T2DM = type 2 diabetes.

^*All tests were performed preoperatively, and at each postoperative visit, the 6-month visit, and at each annual visit.

^†Hypertension percentiles according to the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents. Criteria as used in Alqahtani et al. [9] and adapted from Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report [24].