Figure 2.

Altered cerebellar ALFF and its relationship with behavioral score in patients. (a) Between‐group (all patients vs. HC, LGG vs. HC and HGG vs. HC) differences in ALFF within the cerebellum. Hot and cold colors in the color bar indicate increased and decreased ALFF, respectively, in the patient group (permutation test, FWE corrected p < .05). (b) the scatter plot map displays the significant partial correlation results between increased ALFF (all patients>HC and HGG > HC) and cognitive/linguistic scores. The partial correlation results were obtained after treating education level, glioma WHO grade and tumor volume as covariates. Fitted ALFF and fitted linguistic/cognitive scores indicate the sum of the mean value and the residual value of ALFF and linguistic/cognitive scores after regressing out education level, glioma WHO grade, and tumor volume. In HC group, the WHO grade and tumor volume was set as zero when performing partial correlation analysis. ALFF, amplitude of low‐frequency fluctuation; BNT, Boston naming test; AQ, aphasia quotient [Color figure can be viewed at http://wileyonlinelibrary.com]