Table 2.
Cluster size (mm3) | x (mm) | y (mm) | z (mm) | TFCE | p‐value | |
---|---|---|---|---|---|---|
Local Connectivity | ||||||
ADHD > ND | ||||||
Right superior frontal gyrus | 139,136 | 4 | 54 | 31 | 255.26 | .001a |
Left superior frontal gyrus/right superior frontal gyrus | 0 | 53 | 24 | 249.98 | .001a | |
Left superior frontal gyrus | −8 | 50 | 40 | 249.08 | .001a | |
Right occipital pole/right calcarine cortex | 25,856 | 20 | −92 | 5 | 216.56 | .002 |
Right calcarine cortex | 8 | −92 | 6 | 209.21 | .002 | |
Left calcarine cortex | −8 | −97 | −6 | 199.45 | .002 | |
Right middle frontal gyrus/right opercular part of the inferior frontal gyrus | 9,152 | 36 | 9 | 26 | 201.60 | .002 |
Right middle frontal gyrus/right precentral gyrus | 56 | 18 | 34 | 173.58 | .004 | |
Right middle frontal gyrus | 44 | 18 | 42 | 156.08 | .005 | |
Left medial orbital gyrus/left anterior cingulate gyrus | 10,816 | −12 | 30 | −15 | 142.33 | .007 |
Left medial frontal cortex | −4 | 30 | −19 | 136.70 | .008 | |
Left medial orbital gyrus | −24 | 34 | −15 | 135.82 | .008 | |
Right middle temporal gyrus | 6,848 | 48 | −37 | 2 | 138.80 | .008 |
Right inferior temporal gyrus | 64 | −38 | −22 | 96.54 | .024 | |
Right inferior temporal gyrus | 56 | −30 | −23 | 92.95 | .025 | |
Right parietal operculum/right transverse temporal gyrus | 8,384 | 36 | −27 | 17 | 136.93 | .008 |
Right planum polare | 48 | 3 | −5 | 130.99 | .010 | |
Right planum temporale/right transverse temporal gyrus | 52 | −9 | 0 | 90.79 | .027 | |
Left anterior insula | 2,112 | −32 | 24 | 2 | 113.34 | .015 |
Left frontal operculum | −40 | 16 | 2 | 100.80 | .021 | |
Right parahippocampal gyrus | 448 | 16 | −10 | −24 | 100.29 | .021 |
Right parahippocampal gyrus | 20 | −7 | −33 | 72.27 | .045 | |
Left entorhinal area | 3,776 | −28 | 1 | −37 | 98.54 | .022 |
Left entorhinal area | −32 | −3 | −29 | 94.87 | .025 | |
Left entorhinal area | −20 | −3 | −29 | 82.41 | .035 | |
Left temporale pole | 832 | −52 | 9 | −37 | 87.34 | .030 |
Left temporale pole | −44 | 16 | −42 | 76.19 | .041 | |
Right lingual gyrus/right precuneus | 1,856 | 4 | −56 | 7 | 86.80 | .030 |
Right lingual gyrus/right cerebellum | 20 | −41 | −10 | 74.68 | .043 | |
Right lingual gyrus/right posterior cingulate gyrus | 16 | −49 | −2 | 73.18 | .045 | |
Left caudate | 1,216 | −8 | 16 | 6 | 80.10 | .036 |
Left caudate | −16 | 12 | 10 | 78.44 | .038 | |
Left caudate | −16 | 1 | 19 | 73.45 | .045 | |
Left thalamus proper | 1,280 | −8 | −17 | 0 | 78.23 | .038 |
Left thalamus proper/left caudate | −16 | −12 | 16 | 77.10 | .040 | |
Left thalamus proper | −20 | −21 | 1 | 74.36 | .043 | |
Left angular gryrus | 768 | −44 | −66 | 44 | 76.87 | .040 |
Left middle temporal gyrus | 512 | −64 | 2 | −21 | 75.31 | .042 |
Left middle temporal gyrus | −56 | 1 | −29 | 71.67 | .046 | |
ND > ADHD | ||||||
Right posterior cingulate gyrus/right precuneus | 512 | 20 | −44 | 10 | 169.34 | .005 |
Right middle occipital gyrus/right inferior occipital gyrus | 4,160 | 44 | −72 | 12 | 167.04 | .005 |
Right middle occipital gyrus | 44 | −80 | 17 | 166.61 | .005 | |
Right middle occipital gyrus | 36 | −75 | 20 | 149.88 | .007 | |
Right precuneus/right superior parietal lobule | 15,808 | 4 | −48 | 75 | 163.59 | .005 |
Right posterior cingulate gyrus | 8 | −38 | 38 | 160.77 | .005 | |
Right superior parietal lobe | −8 | −52 | 67 | 148.91 | .007 | |
Left inferior temporal gyrus | 320 | −52 | −19 | −31 | 94.26 | .026 |
Distant Connectivity | ||||||
ADHD > ND | ||||||
None | ||||||
ND > ADHD | ||||||
Right posterior cingulate gyrus | 896 | 20 | −44 | 6 | 168.84 | .006 |
Right fusiform gyrus/right inferior temporal gyrus | 2,048 | 44 | −26 | −19 | 141.92 | .012 |
Right hippocampus | 32 | −22 | −16 | 118.06 | .020 | |
Right hippocampus | 28 | −14 | −16 | 105.83 | .026 | |
Right superior frontal gyrus | 192 | 24 | 20 | 62 | 119.50 | .019 |
Right hippocampus | 384 | 32 | −33 | −3 | 98.20 | .031 |
Right hippocampus/right lingual gyrus | 28 | −41 | −2 | 95.78 | .033 | |
Right cerebellum | 448 | 16 | −67 | −36 | 92.27 | .036 |
Right cerebellum | 24 | −68 | −40 | 85.30 | .043 | |
Left cerebellum | 384 | −28 | −64 | −40 | 89.99 | .038 |
Coordinates are based on MNI152 stereotactic space. Results reported in the table correspond to those clusters above 192 mm3 (three contiguous voxels).
Abbreviations: ADHD = children with attention‐deficit/hyperactivity disorder; ND = neurotypically developing children. TFCE = threshold‐free cluster enhancement; FWE = family‐wise error.
Significant at p < .05 TFCE–FWE level.