Table 3.
Cluster Size (mm³) | x (mm) | y (mm) | z (mm) | TFCE | p‐value | |
---|---|---|---|---|---|---|
Local Connectivity | ||||||
Increases with age in ADHD and Decreases in ND | ||||||
Left postcentral gyrus | 35,584 | −44 | −22 | 41 | 217.03 | .002a |
Left precentral gyrus | −36 | −17 | 49 | 207.50 | .002 | |
Left supramarginal gyrus | −56 | −26 | 41 | 202.97 | .002 | |
Cerebellar vermal lobules | 52,480 | 0 | −46 | −14 | 194.55 | .003 |
Left thalamus proper | −20 | −29 | 1 | 187.25 | .003 | |
Left thalamus proper | −12 | −28 | 9 | 182.88 | .003 | |
Right superior temporal gyrus | 6,656 | 56 | −13 | 0 | 129.26 | .010 |
Right superior temporal gyrus | 64 | −13 | 0 | 108.93 | .017 | |
Right transverse temporal gyrus | 48 | −20 | 4 | 91.29 | .027 | |
Right superior parietal lobule | 17,024 | 28 | −65 | 56 | 126.85 | .011 |
Right superior parietal lobule | 24 | −60 | 67 | 117.94 | .014 | |
Right precentral gyrus | 20 | −19 | 77 | 116.79 | .014 | |
Left frontal pole | 16,000 | −28 | 64 | 3 | 111.35 | .016 |
Left anterior orbital gyrus/left lateral orbital gyrus | −32 | 50 | −20 | 108.26 | .017 | |
Left anterior orbital gyrus/left frontal pole | −24 | 62 | −17 | 101.13 | .021 | |
Right middle cingulate gyrus | 5,632 | 4 | −2 | 35 | 106.83 | .018 |
Right supplementary motor cortex | 8 | 23 | 46 | 104.81 | .019 | |
Right supplementary motor cortex | 12 | 7 | 51 | 98.34 | .023 | |
Left cerebellum | 3,968 | −16 | −87 | −27 | 95.28 | .025 |
Left cerebellum | −8 | −82 | −23 | 91.55 | .027 | |
Left cerebellum | −24 | −91 | −27 | 86.70 | .031 | |
Left anterior cingulate gyrus | 3,840 | −4 | 39 | −4 | 94.47 | .025 |
Left gyrus rectus | 0 | 42 | −24 | 94.34 | .025 | |
Left superior frontal gyrus/left medial frontal cortex | −12 | 51 | −4 | 86.24 | .032 | |
Right anterior insula | 3,392 | 44 | 11 | −10 | 93.19 | .026 |
Right temporal pole/right anterior insula | 44 | 18 | −14 | 90.29 | .028 | |
Right anterior insula/right posterior orbital gyrus | 36 | 23 | −11 | 89.97 | .029 | |
Right supplementary motor cortex | 192 | 12 | −10 | 44 | 91.03 | .028 |
Left superior frontal gyrus | 448 | −20 | 57 | 19 | 82.06 | .035 |
Right supplementary motor cortex | 1,088 | 4 | 16 | 62 | 76.22 | .042 |
Supplementary motor cortex | 0 | 8 | 71 | 73.83 | .045 | |
Left parahippocampal gyrus | 384 | −28 | −15 | −32 | 76.12 | .042 |
Left cerebellum | 192 | −36 | −67 | −32 | 75.45 | .043 |
Left cerebellum | 448 | −32 | −44 | −42 | 74.64 | .045 |
Left cerebellum | −32 | −40 | −50 | 74.07 | .045 | |
Right superior temporal gyrus | 320 | 64 | 7 | −2 | 74.60 | .045 |
Right lateral orbital gyrus | 256 | 44 | 47 | −12 | 71.89 | .047 |
Right precuneus | 192 | 4 | −54 | 43 | 70.34 | .050 |
Increases with age in ND and Decreases in ADHD | ||||||
None | ||||||
Distant Connectivity | ||||||
Increases with age in ADHD and Decreases in ND | ||||||
None | ||||||
Increases with age in ND and Decreases in ADHD | ||||||
Right Supramarginal Gyrus | 448 | 60 | −46 | 38 | 103.7 | .030 |
Effect of the interaction of age and group differences in the degree of local and distant connectivity. Coordinates are based on MNI152 stereotactic space. Results reported in the table correspond to those clusters above 192 mm3 (three contiguous voxels).
Abbreviations: ADHD = children with attention‐deficit/hyperactivity disorder; ND = neurotypically developing children; TFCE = threshold‐free cluster enhancement.
FWE‐corrected p‐value = .051.