Table 2.
Group differences in number of voxels between frontal and subcortical volumes
| Control | bvFTD | |||||
|---|---|---|---|---|---|---|
| Structure | M | SD | M | SD | p value | Effect size |
| DLPFC | 14,054 | 1,521 | 11,759 | 1,487 | <.001 | 1.53 |
| MPFC | 3,359 | 407 | 2,786 | 398 | <.001 | 1.42 |
| OFC | 6,508 | 837 | 5,380 | 819 | <.001 | 1.36 |
| Striatum | 5,286 | 655 | 5,201 | 652 | <.001 | 0.13 |
| Thalamus | 4,555 | 612 | 4,138 | 586 | .029 | 0.70 |
Note. Abbreviations: bvFTD = behavioral variant frontotemporal dementia; DLPFC = dorsolateral prefrontal cortex; MPFC = medial prefrontal cortex; OFC = orbitofrontal cortex.
Estimated marginal mean voxels and significance test from separate linear mixed models, controlling for hemisphere, age, gender, education, and intracranial volume.