Experiment 1 plasma measures and brain gene expression in adult males acquired 45, 90, 180, or 360 min after an intraperitoneal (i.p.) injection of 4 g/kg ethanol (EtOH) or vehicle (VEH). Plasma measures shown include (A) ethanol concentrations and (B) corticosterone. Gene expression outcomes in the hippocampus, amygdala, and spleen are shown for (C, D, E) Interleukin-1β - IL-1β; and (F, G, H) Tumor necrosis factor alpha - TNFα. Letters indicate differences divulged by post hoc testing of a significant main effect of Group (groups that share a letter in common did not differ statistically, whereas differences between groups are indicated by letters that do not match).